Plain-English translation of NCT06029972 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ulcerative Colitis research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new medication called to see if it works better than a placebo (inactive pill) for people with moderate to severe ulcerative colitis — a condition that causes inflammation and sores in the colon. Researchers want to find out if this medication can help reduce symptoms and improve quality of life for patients who haven't responded well to other treatments. The study will track how well the medication works and whether it's safe to use.
Many people with ulcerative colitis stop responding to current treatments or don't get enough relief from their symptoms. This trial is exploring whether this new medication could offer another option for patients who need better disease control.
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If you join, you'll take the study medication (or placebo) for 12 weeks and have your symptoms checked at week 12 to see if you're responding. If you improve, you'll continue on a different dose of the medication for up to 40 more weeks. If you don't respond after 12 weeks, you have the option to try another 12 weeks of treatment before deciding whether to continue. Throughout the study, you'll have regular visits for blood tests, symptom assessments, and possibly colonoscopies to monitor your progress.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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