Plain-English translation of NCT06033950 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing whether a medication called can help people with heart failure (specifically, a condition where the heart's pumping strength has weakened) who cannot take the standard treatments usually prescribed for this condition. You would receive either or a placebo (a pill with no active medication), and researchers would track how well it works and whether it is safe.
Many people with weakened heart function cannot tolerate or are not eligible for the standard heart medications available today. This trial exists to see if this medication might offer a new treatment option for these patients who currently have limited choices.
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You would be randomly assigned to take either or a placebo pill (neither you nor the researchers would know which one you are receiving). You would visit the study center regularly for check-ups, blood tests to monitor your kidney function and potassium levels, and to report how you are feeling. The study involves about 2,600 participants worldwide and will continue until enough data has been collected to determine whether the medication is effective and safe.
AI-generated summary from trial data · Jul 13, 2026 · Not medical advice
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