Plain-English translation of NCT06044935 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how nicotinamide riboside affects your body's ability to burn fat while you sleep on a ketogenic (low-carb) diet. This study will compare the medication to a placebo (dummy pill) and measure changes in your sleeping energy expenditure and fat burning. You'll follow different eating patterns and take either the supplement or a placebo while researchers track how your body responds.
Ketogenic diets are known to change how your body uses energy and burns fat, but scientists don't fully understand whether adding this supplement makes those effects stronger. This research could help explain new ways to support metabolism and weight management.
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You will spend time on two different diets: first a standard high-carb diet, then a low-carb ketogenic diet. During each diet phase, you'll take either the supplement or a placebo (you won't know which). Researchers will measure your sleeping energy expenditure and fat burning using specialized equipment, and you'll complete visits where they collect blood samples, assess your body composition, track your sleep and activity, and monitor various hormones and metabolic markers. The study involves cycling at moderate intensity and following the study diet carefully throughout the duration of your participation.
AI-generated summary from trial data · Oct 5, 2026 · Not medical advice
United States