Plain-English translation of NCT06048159 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a treatment called high-definition transcranial alternating current stimulation (HD-tACS) — a safe, noninvasive way to stimulate the brain using electrical currents delivered through electrodes on the scalp. The treatment is combined with specialized speech therapy focused on short-term memory for words. Researchers want to see if this combination can help stroke survivors who have aphasia (difficulty with speaking, understanding, reading, or writing) recover better language skills.
Stroke often damages the brain areas responsible for language and memory, leaving people with long-lasting communication problems. Current speech therapy treatments help, but the benefits are modest. This trial explores whether adding noninvasive brain stimulation to therapy might boost recovery by helping the brain rebuild connections damaged by the stroke.
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You would be randomly assigned to receive either real brain stimulation or sham (fake) stimulation paired with speech therapy focused on short-term memory. During each session, electrodes would be placed on your scalp, and gentle electrical stimulation would be delivered for about 20 minutes while you participate in language therapy exercises. The study also involves brain imaging scans (MRI) and possibly magnetoencephalography (MEG) to measure how your brain changes during treatment. The research team will work with you to understand the full schedule of visits and duration before you enroll.
AI-generated summary from trial data · Jul 13, 2026 · Not medical advice
United States
Sponsor
Medical College of Wisconsin
Enrollment target
~120 participants
Started
November 2023
Primary completion
January 2033
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Sidney E Schoenrock, MA
Medical College of Wisconsin
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.