Plain-English translation of NCT06050109 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is tracking women with early-stage, hormone-sensitive breast cancer who have already completed five years of ovarian function suppression (OFS) treatment. The study compares two groups: women who continue the medication and women who stop it, to see which approach works better for preventing cancer recurrence and is safer over time. Researchers will analyze hospital medical records to understand the long-term benefits and safety of continuing this hormone-suppressing treatment.
Doctors are not sure whether women with early breast cancer should keep taking this medication beyond five years or if stopping is safe and just as effective. This study will help answer that important question by following real patients and their outcomes over time.
You likely qualify if…
You likely don't qualify if…
This is an observational study, meaning you will not be randomly assigned to a group—your doctor will decide whether continuing or stopping the medication is right for you based on your individual situation. Researchers will review your hospital medical records from September 2023 through September 2026 to track how you do over time. You will not need to make extra visits or undergo new tests beyond your regular cancer care appointments.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
China
Sponsor
Hongmei Zheng, PhD
Enrollment target
~1,200 participants
Started
September 2023
Primary completion
September 2028
Age range
18 Years – 60 Years
Sex
Female only
Last updated on clinicaltrials.gov in March 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Hongmei Zheng, Doctor
Study Principal Investigator
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.