Plain-English translation of NCT06050603 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are studying a brain stimulation technique called transcranial magnetic stimulation (TMS) — a non-invasive way to stimulate brain activity using magnetic pulses on the scalp. This trial tests whether guiding TMS with detailed brain imaging scans and real-time brain activity monitoring can make the treatment work better and more consistently. The goal is to understand why this treatment works differently in different people and how to personalize it.
Even though this brain stimulation technique is approved for treating depression and obsessive-compulsive disorder, it only works well in fewer than half of patients, and results vary widely between individuals. Researchers hope that by using advanced brain imaging to precisely target the right brain area and monitoring brain activity in real time, they can make the treatment more reliable and effective.
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You will visit the research center 2–3 times on separate days. During your first visit, you'll have an MRI brain scan (which involves lying inside a scanner while images are taken). During the scan, you'll be asked to rest, watch videos or listen to sounds, and press buttons in response to what you see or hear. The entire visit may take up to about an hour. Depending on the study's goals, you may have additional visits for more brain imaging and stimulation sessions. Before the MRI, you'll need to remove any metal objects like jewelry or keys for safety.
AI-generated summary from trial data · Oct 7, 2026 · Not medical advice
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