Plain-English translation of NCT06052475 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
If you have an older pacemaker (called a right ventricular pacemaker) and have noticed your heart function has gotten weaker, this trial may be for you. Researchers want to know whether upgrading to a modern pacing approach—one that works more like your heart's natural electrical system—helps you feel better and improves your quality of life compared to staying with the traditional pacemaker approach.
Many patients with older pacemakers develop weakened heart function over time because of how the traditional pacemaker sends electrical signals. Modern pacing technology works differently and may prevent or reverse this damage, but doctors don't yet know whether upgrading existing patients actually helps them feel better and live better.
You likely qualify if…
You likely don't qualify if…
If you join, you'll have a surgery to upgrade your pacemaker to the modern technology. After a month of recovery, you'll spend 2 months in a blinded comparison phase (where you won't know which pacing approach is being used), then 6 months in another blinded phase. During each phase, you'll use your phone or computer to report your symptoms monthly, and at the end of each period you'll have heart function tests, a walking test, and answer questions about your quality of life.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
United Kingdom