Plain-English translation of NCT06052826 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether a personalized support program—including physical therapy, nutrition counseling, and education about preventing confusion—helps older adults recover better after CAR-T cell therapy. CAR-T is a powerful cancer treatment that works well but can be hard on the body. Researchers want to see if extra support before and after treatment helps patients stay stronger and more independent.
CAR-T therapy can cause side effects like weakness, confusion, and loss of muscle in older patients, which may affect their ability to function independently. This trial is designed to find out whether giving patients targeted support—through exercise, nutrition, and brain-health education—can prevent or reduce these problems.
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You will be randomly assigned to either a support group or standard care. If you are in the support group, you will meet with a physical therapist and a dietitian before your chemotherapy starts and multiple times during your hospital stay and first month after CAR-T infusion. You will also receive education about preventing confusion. You will be asked about your physical function, quality of life, and recovery at visits up to 100 days after treatment, and then followed for one year to track your overall health and how well the CAR-T therapy is working.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
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