Testing a new device to improve blood flow after stroke treatment

Plain-English translation of NCT06052969 on ClinicalTrials.gov ↗ · Source last updated August 2025 · Translation generated July 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This early feasibility study is testing a new device called Pulse NanoMED in patients who have suffered an acute ischemic stroke—the most common type of stroke, caused by a blood clot blocking blood flow to the brain. You would be eligible if you've already received standard stroke treatments (clot-busting medication and mechanical thrombectomy, which is a procedure to remove the clot) but still have a partially blocked artery. The study aims to see if this new treatment can improve blood flow to the brain better than current options.

Even after standard stroke treatments, some patients still have incomplete blood flow restoration to their brain, which can limit their recovery and increase disability. This study exists to test whether the Pulse NanoMED device can safely and effectively improve reperfusion—the restoration of blood flow—in these cases.

Do you qualify?

You likely qualify if…

you are between 18 and 85 years old
you have been diagnosed with an acute ischemic stroke caused by a large blood vessel blockage
you have already received standard stroke treatments (clot-busting medication and/or mechanical thrombectomy) but still have a partially blocked artery
your stroke symptoms started less than 9 hours ago
you had no significant disability or functional problems before your stroke
you have a moderate to severe stroke on initial assessment

You likely don't qualify if…

you have a very severe stroke on admission (NIHSS score above 25)
you have bleeding in your brain or a history of bleeding disorders
you are pregnant, breastfeeding, or have a positive pregnancy test
you have a known allergy or sensitivity to iron or contrast dye
you have significant kidney disease or require dialysis

What participation looks like

If you are enrolled, you will receive the Pulse NanoMED procedure as an additional treatment after your standard stroke care in the hospital. The procedure will be performed by the medical team caring for you in the emergency or intensive care setting. You will be closely monitored during and after the procedure, with imaging studies and clinical assessments to evaluate how well the treatment worked and how you recover over time.

AI-generated summary from trial data · Jul 4, 2026 · Not medical advice

Trial locations(1 site)

United States

University of South Carolina - Prisma, Columbia, South Carolina