Plain-English translation of NCT06053567 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether exercise can help people quit smoking, especially those who feel anxious during the quitting process. All participants receive standard smoking-cessation support (counseling and nicotine replacement therapy like patches or gum). You would also be randomly assigned to either higher-intensity or lower-intensity aerobic exercise—both safe, structured programs—to see which approach works best at helping you stay smoke-free.
Many smokers who experience high anxiety struggle to quit because withdrawal symptoms and anxiety can feel overwhelming. This trial is testing whether adding exercise to standard treatment can help reduce anxiety and cravings, making it easier to successfully quit smoking.
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You would receive counseling and nicotine replacement therapy from the study team, and you would be randomly assigned to exercise either 75 minutes per week at higher intensity (60–85% of your heart rate capacity) or lower intensity (20–40% of your heart rate capacity). The exercise takes place at a participating YMCA facility near you. Throughout the study, you would have regular check-ins with the team to support your quit attempt and track your progress.
AI-generated summary from trial data · Jun 20, 2026 · Not medical advice
United States