Plain-English translation of NCT06053671 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are studying genetic changes in brain tissue from people with a specific type of epilepsy called focal cortical dysplasia type IIA/B. The study looks for changes in genes related to something called the mTOR pathway, which may be involved in causing this type of epilepsy. By understanding these genetic changes better, the research team hopes to develop new treatments in the future.
Currently, doctors don't fully understand what causes focal cortical dysplasia epilepsy or how to predict which patients will respond to surgery. This study aims to discover the genetic basis of the condition so researchers can test whether medications that target the mTOR pathway might help prevent seizures in the future.
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If you are having epilepsy surgery, researchers will collect small samples of your blood and cells from inside your nose using a gentle brush swab. If you've already had surgery, you may provide these same samples at a hospital visit. The brain tissue sample comes from tissue that is already being removed during your epilepsy surgery for medical reasons. Researchers will analyze these samples to look for genetic changes and understand how your epilepsy develops.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
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