Plain-English translation of NCT06059690 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
Researchers are testing whether advanced imaging scans—combining PET scans and specialized MRI sequences—can accurately detect and measure how aggressively glioblastoma cells are consuming energy. The study will compare what these imaging scans show with actual tissue samples taken during your planned surgery, to see if the scans can reliably identify the most active tumor cells.
Glioblastoma is a very aggressive brain cancer, and doctors need better tools to see exactly where the most dangerous tumor cells are hiding—including cells that may not show up on standard imaging. This research could help doctors target surgery and treatment more precisely in the future.
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Before your planned surgery, you will have two imaging scans: a standard PET scan and a specialized MRI scan (which will take about 15 minutes longer than usual). During surgery, doctors will collect small tissue samples from your tumor using a special needle and also measure the acidity level in the tumor tissue. After surgery, your tissue samples will be analyzed in the lab to compare with what the imaging showed.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
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