Plain-English translation of NCT06062303 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Septic shock is a life-threatening condition where a severe infection causes your body's blood vessels to fail, cutting off blood flow to vital organs. This trial is testing whether doctors can improve survival by personalizing treatment based on a simple bedside test called capillary refill time—which shows how quickly blood returns to your fingertip after gentle pressure—rather than using a one-size-fits-all approach. The goal is to give each patient exactly the right amount of fluids and medications their body needs, avoiding both under-treatment and dangerous fluid overload.
Many septic shock patients receive too much or too little fluid, which can harm recovery. Doctors currently don't have a reliable, simple way to tell which patients truly need more fluids versus which need medication to strengthen their blood vessels, leading to confusion and sometimes worse outcomes.
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If you are admitted to the hospital with septic shock, you would be randomly assigned to either receive standard care or care guided by the capillary refill time test. In the test-guided group, doctors would periodically check how quickly blood returns to your fingertip and measure your pulse pressure, then use this information to decide whether you need more fluids, blood vessel-strengthening medication, or heart imaging. The study lasts 6 hours from when you enter the trial, during which you'll receive close monitoring and standard medical care while the research team tracks your response to treatment.
AI-generated summary from trial data · Aug 26, 2026 · Not medical advice
France