Plain-English translation of NCT06063538 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Atrial Fibrillation research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new approach to prevent a common complication after heart surgery called atrial fibrillation—an irregular heartbeat that can develop in the days following surgery. The study uses a special pericardial (heart sac) patch combined with amiodarone, an FDA-approved medication that helps regulate heart rhythm. The patch is placed directly on the heart during surgery to deliver the medication right where it's needed.
Irregular heartbeat after heart surgery affects many patients and can lead to serious complications and longer hospital stays. This study is exploring whether delivering this medication directly to the heart during surgery, rather than through the bloodstream, might be a more effective way to prevent this problem.
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If you are enrolled, the treatment would be applied during your scheduled heart surgery—the surgeon would place the special patch with the medication on your heart as part of the operation. After surgery, your heart rhythm would be monitored continuously with an electrocardiogram (EKG) until you leave the hospital, and you may be given a home heart monitor to wear after discharge if needed. The study is focused on what happens during and immediately after your surgery, rather than requiring long-term follow-up visits.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
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