Testing a New Lung Imaging Technique in Children With Cystic Fibrosis

This pilot study is testing a new imaging technique called 19F MRI that uses a special inert gas called perfluoropropane to help doctors see how air moves through children's lungs. The researchers want to know whether this imaging method works safely and effectively in children, and whether it can detect early signs of lung problems in children with cystic fibrosis who have mild or no symptoms. They'll compare results from children with cystic fibrosis to healthy children to understand what normal looks like.

Current lung function tests don't always catch early, subtle lung changes in cystic fibrosis. This new imaging technique could provide clearer pictures of how air moves through the lungs and might help doctors spot problems earlier, before they become serious, so children can get help sooner.