Understanding muscle weakness and multiple health conditions in aging

This research project, called OPTIMA-C, is looking at how muscle loss (sarcopaenia) and living with multiple health conditions at the same time affect frailty in older adults. The study will use muscle ultrasound scans, physical exams, and digital monitoring tools to understand which patients are at highest risk and what early signs might predict how well they recover.

Many older people develop frailty—a state of weakness that makes them more likely to fall, lose independence, and have serious health problems. This trial exists to identify early warning signs of muscle loss and understand how managing multiple conditions together might prevent or slow down frailty.