Plain-English translation of NCT06073886 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a brain stimulation treatment called continuous theta-burst stimulation (cTBS) for people struggling with long-lasting concussion symptoms. Researchers have found that people with persistent symptoms after a concussion tend to have overactivity in a specific brain circuit that connects the front of the brain (which helps with decision-making and emotion control) to a deeper area (which processes emotions). The study will deliver targeted stimulation to this area over the forehead for 10 days to see if it can calm this overactive circuit and improve symptoms.
Most people recover quickly from a concussion, but some experience months or years of ongoing problems like headaches, dizziness, trouble concentrating, anxiety, and irritability—with no proven treatment available. This trial exists to test whether this noninvasive brain stimulation approach might finally offer relief for these patients.
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You will first undergo brain imaging scans to map your individual brain circuit and identify the exact location for treatment. Then, over 10 days, you will receive the brain stimulation treatment delivered through a coil placed against your forehead—this is noninvasive and painless. You may also participate in exposure-based activities as part of the treatment. Researchers will track your symptoms before, during, and after the 10-day period to see if the treatment helps reduce your concussion-related problems.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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