Plain-English translation of NCT06080503 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is comparing two different ways to deliver radiation therapy to treat early-stage laryngeal cancer. One approach uses a newer, faster schedule that delivers higher doses over just 5 treatments, while the other uses the traditional approach spread over many more visits. Both are designed to kill cancer cells, but doctors want to see if the faster option works just as well while potentially reducing side effects.
Standard radiation therapy for laryngeal cancer requires many weeks of treatment, which can be burdensome for patients. This trial exists to test whether a much shorter, more intense radiation schedule can achieve the same results, potentially improving quality of life and convenience for people being treated.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you'll be randomly assigned to receive either the faster radiation schedule (5 treatments over 1-2 weeks) or the standard schedule (28-29 treatments over 6 weeks). You'll have baseline visits to confirm your eligibility, including imaging scans and voice/quality-of-life questionnaires. During treatment, you'll receive radiation therapy on an outpatient basis. After treatment ends, you'll return for follow-up visits at 2 weeks, 3 months, and 12 months to check how well the treatment worked and assess any side effects.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Sponsor
University of Texas Southwestern Medical Center
Enrollment target
~67 participants
Started
March 2024
Primary completion
November 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
David J Sher, MD,MPH
University of Texas Southwestern Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.