Plain-English translation of NCT06082323 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
Researchers are testing a new medication called LT-002-158 by giving it to healthy adults in carefully controlled doses to see how safe it is and how the body handles it. This is the very first time this medication is being given to humans. The study has three parts: testing a single dose, testing how food affects the medication, and testing repeated doses over 14 days.
Before this medication can be tested in patients with skin conditions like hidradenitis suppurativa or atopic dermatitis, researchers need to understand if it is safe and well-tolerated in healthy people first. This early-stage study provides essential information about dosing and safety.
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Depending on which part of the study you join, you may take a single dose of the medication (or placebo), take the medication with different meals to see how food affects it, or take the medication daily for 14 days. You will visit the clinic multiple times for blood tests, vital sign checks, and heart monitoring (EKGs). The entire process takes several weeks, and you will be asked to follow specific instructions about food and other medications.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
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