Plain-English translation of NCT06089603 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This study investigates whether CPAP (a breathing machine worn during sleep) can help lower red blood cell counts in people who have both obstructive sleep apnea and polycythemia (abnormally high red blood cells). Sleep apnea causes repeated breathing interruptions at night, which can trigger your body to overproduce red blood cells. The trial will compare people using CPAP with people receiving standard care alone to see if the breathing machine can reverse this problem.
When you have sleep apnea, your blood oxygen drops repeatedly during sleep, and your body responds by making too many red blood cells. This can thicken your blood and increase stroke or heart attack risk. Doctors think that treating the sleep apnea with this device might naturally reduce those excess red blood cells, but this hasn't been proven yet.
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You will be randomly assigned to either use CPAP nightly along with your regular diet and medications, or to continue your regular diet and medications alone. Over 12 months, you'll visit the clinic at 12 weeks, 24 weeks, and 52 weeks for blood tests (including red blood cell counts), questionnaires about sleep and quality of life, and measurements of your height and weight. If you're in the CPAP group, the doctors will check that you're using the machine correctly and track how often you're using it.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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