Plain-English translation of NCT06090682 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This trial is testing two different brain stimulation approaches — deep brain stimulation (a surgical procedure) and transcranial magnetic stimulation (a non-invasive treatment) — to see if they can help improve thinking and memory problems in people with Parkinson's disease. Researchers will use advanced brain imaging to understand how these treatments work and help them choose the best approach for each person. The goal is to find ways to treat both the movement symptoms and the cognitive (thinking and memory) problems that can come with Parkinson's disease.
Many people with Parkinson's disease experience problems with memory and thinking that can be as disabling as the movement symptoms, but there are fewer treatment options available for these cognitive problems. This trial is trying to understand whether brain stimulation can help with these thinking and memory difficulties, and to figure out which patients might benefit most from each type of treatment.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will be assessed for either deep brain stimulation surgery or transcranial magnetic stimulation (a non-invasive treatment), depending on whether surgery is appropriate for you. Before and after your treatment, researchers will use brain imaging scans and cognitive tests to measure any changes in your thinking and memory. Throughout the study, doctors will track how your symptoms change and analyze brain network patterns to understand how the treatment is helping.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
China
Sponsor
Tianjin Huanhu Hospital
Enrollment target
~200 participants
Started
November 2023
Primary completion
November 2026
Last updated on clinicaltrials.gov in October 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Zhao Guangrui, doctor
Tianjin Huanhu Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.