Plain-English translation of NCT06092554 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a four-strain probiotic supplement called LactoLevure can help prevent ventilator-associated pneumonia (a serious lung infection) in critically ill patients who need breathing machines after trauma or stroke. About 186 patients will receive either the probiotic medication or a placebo (inactive pill) while on a ventilator in the intensive care unit. Early research suggests this treatment may reduce the risk of developing this infection, but doctors need more evidence to be sure it works.
Ventilator-associated pneumonia is a serious complication that affects many patients on breathing machines and has a very high death rate. While doctors have several proven ways to reduce this infection, the medication being tested hasn't been officially added to those recommendations yet—but recent studies suggest it might help, particularly in patients with brain injuries.
If you qualify and agree to participate, you will be randomly assigned to receive either the probiotic supplement or a placebo in capsule form while you are in the intensive care unit on a breathing machine. The study team will monitor you to see whether you develop the lung infection and track your overall recovery. Your participation continues while you are hospitalized and on the ventilator, with follow-up assessments of your health outcomes.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
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