Plain-English translation of NCT06094205 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing the BrainGate2 Neural Interface System, an implanted medical device designed to help people who have lost the ability to speak due to serious neurological conditions like ALS, stroke, or spinal cord injury. The device is placed in the part of your brain that controls speech and reads your brain activity when you try to speak—even though your body can't move. By translating these brain signals into words on a screen, the device bypasses the injured nerves and gives you back a way to communicate.
Many people with conditions like ALS, stroke, or severe spinal cord injury lose the ability to speak but their mind remains sharp and active. This trial exists to develop a way to restore communication for these individuals by directly reading speech intention from the brain, offering hope to those who are otherwise locked in their own bodies.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would undergo surgery to have the BrainGate2 sensor implanted into the speech area of your brain. After the implant heals, you would attend regular visits at the research center (within three hours of your home) where the device would be programmed and you would practice using it to convert your thoughts into spoken words or text. The research team would work with you over many months to refine how well the device understands your speech intentions.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
United States
Sponsor
Leigh R. Hochberg, MD, PhD.
Collaborators
National Institute on Deafness and Other Communication Disorders (NIDCD)
Enrollment target
~2 participants
Started
October 2023
Primary completion
August 2027
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Leigh R. Hochberg, M.D., Ph.D.
University of California, Davis
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.