Plain-English translation of NCT06096688 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →This study is collecting tissue and blood samples from people who have hereditary cancer syndromes (inherited conditions that increase cancer risk) as well as from people with average cancer risk. Researchers will use these samples to grow miniature versions of intestinal and endometrial tissue in the laboratory to better understand why some people develop colorectal or endometrial cancer, and to identify new genes and proteins that could be targeted with future treatments.
About one in four people diagnosed with colorectal or endometrial cancer have a family member who was also diagnosed with these cancers, suggesting these diseases have a strong genetic component. This study exists to discover new genes responsible for cancer risk and to identify new targets for precision medicine—personalized treatments based on a person's unique genetic makeup.
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Your participation involves having tissue and blood samples collected during a medical procedure you are already scheduled to have—such as a colonoscopy, endoscopy, endometrial biopsy, or cancer surgery at Weill Cornell Medicine. The researchers will collect normal tissue, polyp tissue (if present), and tumor tissue (if applicable), along with blood samples. These samples will be stored and used for future research studies to understand cancer biology and develop new treatments.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States
Sponsor
Weill Medical College of Cornell University
Collaborators
National Cancer Institute (NCI)
Enrollment target
~1,120 participants
Started
May 2019
Primary completion
May 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Steven M Lipkin, MD, PhD
Weill Medical College of Cornell University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.