Plain-English translation of NCT06098586 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether partial wrist denervation—a surgical procedure that reduces pain signals from damaged nerves in the wrist—works better than a guided exercise program for people with wrist arthritis. The exercise program teaches you how to strengthen and stabilize your wrist to use it pain-free during daily activities. Researchers want to know which approach helps patients feel better and regain wrist function over 12 months.
Doctors don't have strong evidence about which treatment works best for wrist arthritis. This trial aims to fill that gap by directly comparing the surgical approach with a non-surgical exercise approach, so patients and doctors can make better-informed decisions.
You likely qualify if…
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You will be randomly assigned to either the exercise group or the surgery group. If assigned to exercise, you'll receive education and a personalized program of strengthening exercises you can do at home, designed to stabilize your wrist and reduce pain during daily activities. If assigned to surgery, you'll have a procedure under local anesthesia performed by a hand surgeon. Both groups will have follow-up appointments over 12 months to measure pain, grip strength, wrist movement, and how well the treatment is working.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
Sweden
Sponsor
Karolinska Institutet
Enrollment target
~140 participants
Started
November 2023
Primary completion
November 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Elin Swärd, MD, PhD
Karolinska Institutet
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.