Plain-English translation of NCT06101069 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After brain radiation therapy, doctors sometimes see growth on imaging scans but cannot easily tell if it is active tumor or just scar tissue from radiation. This study is testing a new MRI scanning method called Magnetic Resonance Fingerprinting (MRF) combined with another imaging technique to help doctors make this distinction without needing surgery. The new scan takes about 5 minutes and could become a much safer way to monitor patients after brain radiation.
Currently, the only way to know for certain whether new brain growth after radiation is active tumor or just radiation damage is through surgery and a biopsy — which is invasive, risky, and not suitable for many patients. This trial aims to develop a non-invasive imaging tool that can give doctors answers without putting patients through surgery.
You likely qualify if…
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If you qualify, you will have one or more specialized MRI brain scans using the new fingerprinting method. The scan takes about 5 minutes for whole brain coverage and is non-invasive — you simply lie in the MRI machine while the scanner takes detailed images. If you have a scheduled biopsy or surgery for your brain condition, the researchers will compare the MRI findings with the tissue samples to validate how accurate the new scan is.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
United States