Plain-English translation of NCT06101693 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Doctors sometimes miss heart failure in people with obesity because the usual blood test (NT-proBNP) doesn't work as well in this group. This study is collecting information from about 1,000 patients in primary care to find better ways to spot heart failure early, no matter a person's weight. Researchers will look at blood and urine samples, heart scans, and medical records to understand which tests work best.
Half of people with obesity who actually have heart failure have normal levels of the standard blood marker used to diagnose the condition. This means many people are either diagnosed late or not at all, which can lead to serious health crises. This research aims to find better diagnostic tools so doctors can catch heart failure sooner and help patients before they become very ill.
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You would visit a study center for heart tests including an electrocardiogram (ECG) and echocardiogram (ultrasound of the heart), blood and urine samples, and a health questionnaire. After that initial visit, the research team will follow your health passively for at least 10 years by checking hospital records and health databases—you won't need to attend additional visits unless the researchers contact you. The goal is to see how often heart failure develops in different groups and how well the new biomarkers predict outcomes.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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