Plain-English translation of NCT06104371 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →This trial is testing whether magnetic tracers (called Magtrace and Magseed) can help surgeons find sentinel lymph nodes — the first nodes where cancer might spread — in breast cancer patients undergoing chemotherapy before surgery. The study wants to see if marking these nodes with the magnetic tracer before chemotherapy helps doctors find the same nodes later during surgery, three to six months later. This matters because chemotherapy might change how fluid drains through the lymph system, and the researchers want to make sure they're tracking the right nodes.
Current treatments use radioactive tracers to find lymph nodes, but magnetic tracers might work better and be safer. This study wants to prove that magnetic markers can work alongside standard methods, and that marking nodes before chemotherapy — rather than after — gives surgeons the most accurate information about where cancer might have spread.
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If you join this study, you will receive a magnetic tracer injection before your chemotherapy begins, then another injection after chemotherapy ends, so doctors can compare how well they work at finding lymph nodes. You may also have a small magnetic clip placed on a marked lymph node if you have cancer in your nodes. You'll then have your standard breast cancer surgery, where the surgeon will use a special magnetic probe to locate the marked nodes. Your regular chemotherapy and surgery follow the current standard treatment plan — this study simply adds these magnetic tracking methods alongside your regular care.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
Sweden
Sponsor
Vastra Gotaland Region
Collaborators
Uppsala University, Region Västmanland
Enrollment target
~459 participants
Started
September 2025
Primary completion
December 2027
Age range
18 Years – 85 Years
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Fredrik AM Warnberg, prof
Vastra Gotaland Region
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.