Plain-English translation of NCT06108089 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are testing a new type of MRI scan that can detect areas of low oxygen in head and neck tumors. This pilot study will help doctors understand whether these special scans can predict which patients will benefit most from chemotherapy combined with radiation therapy, or whether surgery might be a better option. The goal is to eventually use these scans to personalize cancer treatment plans for each patient.
Head and neck cancers don't all respond the same way to treatment. Tumors with low-oxygen areas often respond poorly to chemotherapy and radiation. This study exists to see if the new MRI approach can identify these problem areas before treatment starts, so doctors can adjust your treatment plan to give you the best chance of success.
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If you receive chemotherapy and radiation, you'll have two MRI scans—one before treatment starts and another two weeks into your treatment—plus a special PET scan before starting therapy. If you're having surgery instead, you'll have one MRI scan and one PET scan before your operation, and the surgical specimen will be tested in a lab. The entire study involves imaging appointments over a few weeks, with follow-up scans three months after your main treatment to see how well it worked.
AI-generated summary from trial data · Aug 15, 2026 · Not medical advice
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