Plain-English translation of NCT06110754 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Sickle cell disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers developed and tested I-STRONG for SCD, a new 8-week pain management program designed specifically for teenagers with sickle cell disease and their families. The program combined mind-body techniques like breathing exercises and guided imagery, along with cognitive-behavioral coping skills and gentle movement training. This trial adapted and tested the program with real patients to see if it was practical, acceptable, and helpful for managing chronic sickle cell pain.
Sickle cell disease causes severe pain that affects many teenagers, especially Black youth, and current pain treatments often don't work well enough. Researchers noticed that effective programs for other chronic pain conditions exist, but nothing had been specifically tailored for sickle cell patients and their unique needs, so they created this program to fill that gap.
Participants were divided into two groups. One group took part in in-depth interviews over two sessions to help shape the final program based on their real experiences. The other group participated in the full 8-week I-STRONG program, which involved 16 sessions where they learned and practiced breathing exercises, relaxation techniques, cognitive coping skills, and gentle neuromuscular movements—along with their parents or guardians. Sessions focused on helping teenagers break the cycle of pain, fear of movement, and avoidance that often makes chronic sickle cell pain worse.
AI-generated summary from trial data · Aug 20, 2026 · Not medical advice
United States