Plain-English translation of NCT06115122 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The PEPPI Study is a large research project following pregnant women to understand who is at risk for placental problems—when the placenta doesn't work as well as it should during pregnancy. Researchers will collect blood samples from women at two points during pregnancy (early and late), and some women will also have extra ultrasound scans. By studying these women and their babies over time, researchers hope to find warning signs that can help doctors catch and treat pregnancy complications earlier.
Placental problems can lead to serious pregnancy complications like pre-eclampsia (dangerously high blood pressure), slow fetal growth, and other health issues for both mother and baby. There is no reliable way yet to predict who will develop these problems, so this study aims to identify blood markers and other early signs that could help doctors protect pregnant women and their babies.
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If you enroll, you will have blood drawn twice during your pregnancy—once in the first trimester and once in the third trimester. Depending on which group you are placed in (based on your personal risk factors), you may also have an extra ultrasound scan around 30–32 weeks of pregnancy. After your baby is born, researchers may ask to follow your child's health information through national health records until age 15, and your baby's father may be invited to provide information as well.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
Finland
Sponsor
Oulu University Hospital
Collaborators
PerkinElmer, Inc., Roche Diagnostics GmbH
Enrollment target
~3,000 participants
Started
February 2022
Primary completion
December 2027
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jaana E Nevalainen, Assoc prof
The Wellbeing Services County of North Ostrobothnia
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.