Plain-English translation of NCT06118723 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Glioblastoma research guide →This international study is testing whether removing more of a high-grade brain tumor during surgery—including areas that don't show up as brightly on imaging scans—is safer and more effective than the standard approach of removing only the most visible parts. Researchers will compare how well patients do after each type of surgery, measuring both how long they survive and whether they experience any loss of function like weakness or speech problems.
High-grade brain tumors are aggressive and life-threatening, and doctors want to know whether being more aggressive in removing tumor tissue during surgery might help patients live longer without causing more harm or disability afterward.
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If you join, you will undergo brain surgery with one of two resection approaches—either removing more of the tumor including areas that are less visible on scans, or removing only the most clearly visible parts. After surgery, you will return for follow-up visits at 6 weeks, 3 months, and 6 months to have your strength, speech, thinking abilities, and overall quality of life assessed through various tests and questionnaires. The full study will track you for about 5 years total.
AI-generated summary from trial data · Jul 18, 2026 · Not medical advice
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