Plain-English translation of NCT06120283 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This study is testing a new drug called designed to fight advanced breast cancer and other solid tumors. Researchers want to find the safest dose and learn how well this medication works, either by itself or when combined with other approved cancer drugs. The trial will help determine if this treatment can help patients whose cancers depend on a protein called CDK4.
Current treatments for hormone-receptor-positive breast cancer don't work for everyone, and some patients develop resistance to existing drugs. This trial explores whether this medication could offer a new option for people whose cancers have stopped responding to standard therapies.
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The trial has two main phases. In Phase 1a, researchers will test increasing doses of the medication—either alone or combined with other approved cancer drugs—to find the safest and most effective dose. In Phase 1b, more patients will receive the recommended dose to further study safety and effectiveness. Throughout the trial, you will have regular visits for blood tests, scans, and checkups to monitor how the treatment is working and how you are tolerating it.
AI-generated summary from trial data · Aug 19, 2026 · Not medical advice
United States