Plain-English translation of NCT06124261 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand why women with polycystic ovary syndrome (PCOS)—a condition involving high male hormone levels—often develop fatty liver disease. This study will follow 150 women over time, comparing those with PCOS and high male hormones, those with PCOS and normal hormone levels, and women without PCOS, to see how hormones and fat buildup in the liver are connected.
Fatty liver disease is becoming more common in women with PCOS, but doctors don't fully understand why. This research aims to reveal whether high male hormone levels play a key role in liver damage, which could eventually lead to better prevention and treatment strategies.
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You will be part of a long-term follow-up study where researchers track your health over time through blood tests, imaging scans of your liver, and medical assessments. The study compares three groups of women to see how hormone levels and liver health are related, helping scientists understand whether male hormone patterns contribute to liver injury in PCOS.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Duke University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Enrollment target
~150 participants
Started
January 2024
Primary completion
December 2028
Age range
18 Years – 42 Years
Sex
Female only
Last updated on clinicaltrials.gov in April 2026.
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Central contact
Lily C Carbullido, B.S.
University of California, San Francisco
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