Testing a supplement to slow muscle weakness in ALS

This clinical trial is testing acetyl-L-carnitine, a natural substance that may help protect nerve cells and slow down ALS progression. Researchers want to find out if the medication works, at what dose it works best, and whether it is safe and well-tolerated. The study will compare the medication at two different strengths against a placebo (a dummy pill with no active ingredient) in people with early ALS.

ALS causes progressive loss of muscle strength and function, and current treatments are limited. Scientists believe this medication may support nerve cell energy and reduce harmful inflammation, potentially slowing disease progression—making it worth testing in a rigorous clinical trial.