Plain-English translation of NCT06127264 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how the tightness of the upper cuff on a carbon fiber ankle-foot brace (called a CDO) affects how well it supports your leg and reduces stress on your foot. Right now, there's little guidance on how tight patients should fasten this cuff, so this study will measure the forces inside the cuff at different tightness levels to find the best approach.
If the cuff is too loose, your leg can slip inside the brace and the device won't work as well. If it's too tight, it may be uncomfortable. This study aims to figure out the right balance so patients get the best support and doctors know what to recommend.
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You will visit the lab and complete walking and movement tasks both with and without a leg brace, and while wearing the brace at different cuff tightness levels (loose, moderate, and tight). Sensors will measure the forces inside the cuff as you walk and move. The study compares healthy volunteers to people who already wear leg braces, with or without nerve damage.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
United States
University of Iowa
Enrollment target
~60 participants
Started
March 2024
Primary completion
December 2026
Age range
18 Years – 90 Years
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jason M Wilken, PT, PhD
University of Iowa
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.