Plain-English translation of NCT06127342 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our PTSD research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether doing moderate-intensity exercise (like biking) right after trauma-focused therapy can help people with PTSD recover better. Researchers believe that combining exercise with therapy may help the brain strengthen its ability to learn that traumatic memories are no longer a threat. The study will compare moderate-intensity exercise to low-intensity exercise to see which approach works best.
People with PTSD from interpersonal violence often struggle with traditional therapy alone. This research explores whether adding exercise right after therapy sessions can enhance the brain's natural healing process and help reduce PTSD symptoms more effectively.
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You would attend three visits over two days. At your first visit, you'll complete screening tests and write down memories of your traumatic experience. At your second visit, you'll have a brain scan, then recall your trauma while your brain activity is measured, and then either do 30 minutes of moderate-intensity biking or low-intensity biking depending on which group you're in. You'll return 24 hours later for a final visit where you'll repeat the trauma recall task with another brain scan to see how your brain's response has changed.
AI-generated summary from trial data · Jun 23, 2026 · Not medical advice
United States