Plain-English translation of NCT06128278 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a plant-based supplement called to see if it can improve how well blood vessels work in postmenopausal women. Some women have chronic kidney disease, which can damage blood vessels and increase heart disease risk. Researchers want to find out if this medication might help protect blood vessel health, especially in women whose kidneys aren't working as well as they should.
Women with kidney disease face a much higher risk of heart and blood vessel problems, partly because declining kidney function and hormonal changes during menopause both harm blood vessel health. Hormone replacement therapy is risky for long-term use, so researchers are exploring whether this medication—which acts similarly to estrogen in the body—could safely improve blood vessel function without those risks.
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You will attend two separate study visits, spaced apart by at least a week or two. At one visit, you'll take the plant-based supplement; at the other visit, you'll take a placebo (inactive pill), with the order assigned randomly. At each visit, researchers will measure how well your blood vessels function using ultrasound and other non-invasive tests to see if the medication makes a difference.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States