Plain-English translation of NCT06129838 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Alzheimer Disease research guide →This research study is testing a new imaging tracer called that helps doctors see inflammation in the brain using a special type of scan called PET imaging. Researchers want to compare brain inflammation patterns between people with normal memory and people who have been diagnosed with Alzheimer's disease or related dementia. This tracer may help doctors better understand how inflammation contributes to memory loss and cognitive decline.
Inflammation in the brain is thought to play an important role in Alzheimer's disease, but doctors don't have good ways to see and measure it yet. This study aims to develop and test a new imaging tool that could help identify inflammation early and eventually lead to better treatments.
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If you enroll, you will receive a single injection of the imaging tracer into a vein, and then undergo a PET scan of your brain and neck. The scan allows researchers to see how the tracer distributes in your brain. The entire visit will likely take a few hours, and you will be compared to either healthy participants or others with cognitive impairment to help researchers understand how inflammation differs between groups.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
United States
Sponsor
Washington University School of Medicine
Enrollment target
~80 participants
Started
May 2023
Primary completion
May 2027
Age range
50 Years and older
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jayashree Rajamanickam
Washington University School of Medicine
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.