Plain-English translation of NCT06137365 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This clinical trial is testing oral (a gummy containing THC, the active ingredient in ) to see if it can help people with obesity lose weight. Half of the participants will receive the active medication, starting at a low dose and gradually increasing it over the trial. The other half will receive a placebo gummy that looks identical but contains no active ingredient, so researchers can fairly measure whether the medication actually works.
Obesity is a serious health challenge, and current weight loss medications don't work for everyone or may have side effects that people can't tolerate. This trial is exploring whether this medication might offer a new option for helping people achieve weight loss.
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You would visit the research center for screening and check-in appointments, then take one gummy daily for six months—either the active medication (starting at 5 mg and increasing gradually every three weeks) or placebo. You would use your phone or tablet to track information about your health and weight loss progress. The study involves regular check-ins with the research team to monitor your health and how you're responding to the treatment.
AI-generated summary from trial data · Aug 15, 2026 · Not medical advice
United States
Phase
Testing effectiveness
Sponsor
Joshua A. Lile, Ph.D.
Enrollment target
~40 participants
Started
August 2026
Primary completion
March 2028
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in August 2026.
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Central contact
Joshua Lile
Joshua A. Lile, Ph.D.
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.