Plain-English translation of NCT06140875 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Glioblastoma research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a noninvasive radiofrequency electromagnetic field treatment can be safely combined with standard brain cancer treatment. Newly diagnosed glioblastoma patients will receive the usual chemotherapy and radiation therapy, plus three sessions per week of this radiofrequency treatment during the initial phase, then twice weekly during maintenance chemotherapy.
While earlier studies suggest radiofrequency electromagnetic field treatment may help glioblastoma patients with fewer side effects, there is limited prospective data on how well it works when combined with the standard first-line chemotherapy and radiation approach. This trial aims to fill that gap and determine if this combination is feasible and effective.
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After surgery, you will start the standard six-week course of radiation therapy combined with chemotherapy. During this time, you will also receive radiofrequency electromagnetic field treatment three times per week for 60 minutes each session. After the initial phase, you will continue with maintenance chemotherapy for six cycles (one cycle every 28 days), during which you'll receive the radiofrequency treatment twice per week on the first five days of each cycle. In total, you will receive 30 radiofrequency treatment sessions over several months.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
Germany
Sponsor
Charite University, Berlin, Germany
Enrollment target
~26 participants
Started
November 2023
Primary completion
May 2029
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in February 2025.
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Central contact
Pirus Ghadjar, Prof. Dr.
Charite University, Berlin, Germany
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.