Plain-English translation of NCT06141525 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing remote ischemic conditioning (RIC)—a simple technique where a blood pressure cuff on your arms is inflated and deflated repeatedly—to see if it can reduce heart damage in patients undergoing off-pump bypass surgery. Researchers will compare patients who receive the full treatment with those who receive a cuff at lower pressure (a control group). The goal is to learn whether this treatment can help patients recover better and avoid serious heart problems in the first three months after surgery.
When the heart is temporarily deprived of blood during surgery and then blood flow returns, it can cause injury to heart tissue. This treatment has shown promise in reducing that kind of injury in other organs, but doctors don't yet know if it works specifically for patients having bypass surgery without being put on a heart-lung machine.
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If you join this trial, you will be randomly assigned to either the active treatment group or the control group. The active group will receive cuff exercises on both upper arms three days before surgery and for seven days after surgery—the cuff inflates and deflates to briefly reduce blood flow. The control group will have the same cuff placed, but it will only be pressurized to a low level. You will be followed for three months after surgery, with doctors monitoring you for any serious heart-related events like heart attack, stroke, or need for additional surgery.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
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