Plain-English translation of NCT06145711 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson's Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new approach to Parkinson's disease using stem cells derived from your own body. Researchers will grow special dopamine-producing brain cells from your cells in the laboratory, then surgically transplant them into a specific area of your brain that controls movement. The goal is to see if this treatment is safe and whether it can help reduce Parkinson's symptoms.
Current Parkinson's medications often lose effectiveness over time, leaving patients with symptoms that are difficult to control. This trial is exploring whether replacing damaged dopamine-producing cells with new ones grown from stem cells might offer a new treatment option for people whose medications no longer work well.
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You will undergo surgery under general anesthesia to have stem cells injected into one side of your brain using a precise stereotactic technique. After surgery, you will have regular check-ups over 6 months to monitor safety and how well the treatment is working. If the first 6 months show good safety and some benefit, you may continue for another 6 months; if safe but not yet effective, you may receive a second transplant on the other side of the brain and be followed for up to 24 months total.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
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