Plain-English translation of NCT06146764 on ClinicalTrials.gov ↗ ·
Doctors use ultrasound to find lumps (nodules) in the thyroid gland, but sometimes it's hard to tell if these lumps are cancer or not. This study is testing whether adding a special type of ultrasound called contrast-enhanced ultrasound—which shows blood flow in the nodule—can help doctors make better decisions about which nodules need a biopsy. Researchers are comparing two different scoring methods to see which one works better at catching thyroid cancer while avoiding unnecessary biopsies.
Currently, there is no standard way to combine regular ultrasound with contrast-enhanced ultrasound to diagnose thyroid cancer, which means doctors may order too many biopsies or miss some cancers. This study aims to find the best scoring method so doctors can more accurately tell benign nodules from cancerous ones.
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This is a retrospective study, meaning researchers will review your existing medical records, ultrasound images, and biopsy results from your past care—you will not need to undergo new procedures or make additional visits. Researchers will analyze your imaging data using two different scoring methods to compare how well each one identifies whether your thyroid nodule was cancer or not.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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