Recruiting

Brain Training and Acupuncture for Fibromyalgia Pain Relief

Plain-English translation of NCT06157866 on ClinicalTrials.gov ↗ · Source last updated October 2025 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

Researchers are studying whether a special type of cognitive training combined with acupuncture can help people with fibromyalgia manage their chronic pain. The study uses advanced brain imaging to understand how the relationship between a patient and their care provider—especially feelings of trust and understanding—might help reduce pain. This research could lead to new, non-medication ways to treat fibromyalgia.

Fibromyalgia causes widespread chronic pain and needs better treatment options beyond medication. Scientists have discovered that the bond between patients and their healthcare providers activates certain parts of the brain that may naturally reduce pain. This trial explores whether strengthening that connection through training and acupuncture can help people with fibromyalgia feel better.

Do you qualify?

You likely qualify if…

you have been formally diagnosed with fibromyalgia using standard medical criteria
you have had fibromyalgia pain for at least 6 months
your baseline pain level is at least 4 out of 10
you have been on stable doses of your current medications for at least 30 days and are willing to keep them unchanged during the study
you are able to understand and consent to the study procedures

You likely don't qualify if…

you have a history of serious mental health conditions, including psychosis, bipolar disorder, or severe personality disorders
you have had significant anxiety or panic disorder that could interfere with brain imaging scans
you have metal implants, a heart pacemaker, or are unable to have an MRI scan for any reason
you are currently taking opioid pain medications
you have received formal meditation training recently or have other chronic pain conditions that are more severe than your fibromyalgia

What participation looks like

You would be randomly assigned to receive either specialized cognitive training or fibromyalgia education from a pain specialist. Both groups would also receive acupuncture treatment. During the study, you would undergo brain imaging scans (MRI) while interacting with your care provider so researchers can measure how your brains synchronize. The study involves multiple visits and requires you to avoid certain substances like marijuana and nicotine before scanning appointments.

AI-generated summary from trial data · Jun 6, 2026 · Not medical advice

Trial locations(3 sites)

United States

Massachusetts General Hospital, Charlestown, Massachusetts

Spaulding Rehabilitation Hospital, Charlestown, Massachusetts

Brigham and Women's Hospital, Chestnut Hill, Massachusetts