Plain-English translation of NCT06158503 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Type 1 Diabetes research guide →This research explores how better blood sugar control affects bone health in people living with type 1 diabetes. Researchers will enroll 25 adults who are already planning to start using an automated insulin delivery system (sometimes called an artificial pancreas) and measure bone markers in their blood before and after starting the device. The study aims to understand whether improving blood sugar levels and reducing blood sugar swings can help strengthen bones and reduce fracture risk.
People with type 1 diabetes have weaker bones and break bones more easily than others, even though standard bone density tests don't always show why. Doctors know that high blood sugar and unstable blood sugar levels damage bones, but it's unclear whether getting better control with newer insulin devices can reverse this damage and protect bones.
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You will have three study visits: one before you start the automated insulin device, one at 2 months after starting it, and one at 4 months. At each visit, researchers will take blood samples to measure bone markers and collect information about your blood sugar control from your device. The study lasts 4 months total, and your main responsibility is to use the automated insulin system as planned and share your glucose monitoring data with the research team.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Canada
Sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Collaborators
Laval University, Institut de Recherches Cliniques de Montreal
Enrollment target
~25 participants
Started
February 2025
Primary completion
December 2026
Age range
18 Years – 100 Years
Last updated on clinicaltrials.gov in February 2025.
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Central contact
Elisabeth Nguyen
IRCM
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