Plain-English translation of NCT06160128 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying how well several COVID-19 medications—including nirmatrelvir-ritonavir and molnupiravir—work for Veterans in the VA healthcare system. By looking at medical records from thousands of Veterans who had COVID-19, the team wants to learn which treatments are most effective and help improve care for future patients.
When COVID-19 was new, doctors had many medication options but weren't sure which ones worked best or who benefited most. This study exists to answer those questions using real-world information from the VA system, so future patients get the most helpful treatment.
You likely qualify if…
You likely don't qualify if…
This is not a traditional study where you visit a clinic. Instead, researchers will review your existing VA medical records to see whether you received COVID-19 treatment and what happened afterward. No visits, injections, or new medications are required—you're simply allowing the research team to use information already in your health records to improve care for Veterans.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Collaborators
Biomedical Advanced Research and Development Authority, Food and Drug Administration (FDA)
Enrollment target
~400,000 participants
Started
September 2022
Primary completion
September 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kristina L Bajema, MD
VA Portland Health Care System, Portland, OR
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.