Plain-English translation of NCT06160635 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
D-SOLVE is a large research study involving hospitals across Europe that aims to understand why hepatitis D affects different people in different ways. Researchers will collect blood samples, sometimes tissue samples from the liver, and detailed medical information from up to 750 people who have chronic hepatitis D infection. By studying these samples and records, the team hopes to figure out which patients are most likely to benefit from treatments that already exist.
Hepatitis D is a serious liver infection, but doctors have noticed that it progresses very differently from person to person—some people stay stable while others develop severe liver damage. This study exists to understand what factors control how each person's body responds to the virus, so doctors can eventually predict who needs treatment most urgently and tailor care to individual patients.
You likely qualify if…
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If you join Cohort A, you'll have a one-time visit where researchers will take blood samples and collect information about your medical history and current liver health. If you join Cohort B, you may either provide old liver biopsy records and follow-up information you already have, or you may be asked to undergo a new small tissue sample from your liver (a procedure called a biopsy or fine-needle aspirate). The study involves visits at one of four major European medical centers, and participation helps researchers build a detailed picture of how hepatitis D behaves across different patient groups.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Germany
Italy
Romania
Sweden