Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.
(54 sites) United States
University of Alabama Medicine (UAB Medicine), Birmingham, Alabama Banner MD Anderson Cancer Center, Gilbert, Arizona UC Irvine Health, Orange, California Rocky Mountain Cancer Centers, LLP, Lone Tree, Colorado Florida Cancer Specialists - South Region Research Office, Fort Myers, Florida Florida Cancer Affiliates - Ocala, Ocala, Florida Florida Cancer Specialists - North Region Research Office, St. Petersburg, Florida Florida Cancer Specialists - East Region Research Office, West Palm Beach, Florida Georgia Cancer Center at Augusta University, Augusta, Georgia Memorial Sloan Kettering Cancer Center - Main Campus, New York, New York Atrium Health Levine Cancer Institute, Winston-Salem, North Carolina Willamette Valley Cancer Institute and Research Center, Eugene, Oregon Oregon Health & Science University, Portland, Oregon Thomas Jefferson University - Center City (Philadelphia), Philadelphia, Pennsylvania Tristar BMT, Nashville, Tennessee The University of Texas M.D. Anderson Cancer Center, Houston, Texas Huntsman Cancer Institute, Salt Lake City, Utah Fred Hutchinson Cancer Center, Seattle, Washington Australia
Royal Adelaide Hospital, Adelaide, South Australia Monash Medical Centre, Clayton, Victoria Peter MacCallum Cancer Centre, Melbourne, Victoria Royal Perth Hospital, Perth, Western Australia France
Centre Léon Bérard, Lyon, Auvergne-Rhône-Alpes Institut Bergonié, Bordeaux Institut Paoli Calmettes, Marseille CHU de Nantes (University Hospital of Nantes) - Hôtel Dieu, Nantes Hôpital Saint Louis, Paris Centre Hospitalier Lyon-Sud, Pierre-Bénite Germany
Universitätsklinikum Aachen, Aachen Charité Campus Virchow-Klinikum - Universitätsmedizin Berlin, Berlin Universitätsklinikum Frankfurt, Frankfurt am Main Medizinische Hochschule Hannover, Hanover Universitätsklinikum Jena, Jena Universitätsklinikum Mannheim, Mannheim Klinikum rechts der lsar der Technischen Universität München, München Italy
Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant'Orsola, Bologna Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan Fondazione IRCCS San Gerardo dei Tintori - SC Centro di Ricerca Fase I, Monza Fondazione IRCCS San Gerardo dei Tintori, Monza New Zealand
Auckland City Hospital, Auckland Christchurch Hospital, Christchurch South Korea
Uijeorigbu Eulji Medical Center, Eulji University, Uijeongbu-si, Gyeonggi-do Hallym University Sacred Heart Hospital, Anyang-si, Gyeonggido Dong-A University hospital, Busan Keimyung University Dongsan Hospital, Daegu Spain
Hospital Universitari Vall d'Hebrón, Barcelona Hospital Clínic de Barcelona, Barcelona Hospital Universitari Germans Trias i Pujol (ICO Badalona), Barcelona Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas Hospital Universitario de La Princesa, Madrid Hospital Universitario Ramón y Cajal, Madrid Hospital Universitario 12 de Octubre, Madrid Hospital de Día Quirónsalud Zaragoza, Zaragoza United Kingdom
Imperial College Healthcare NHS Trust, London, England