Plain-English translation of NCT06163482 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Cystic Fibrosis research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This study is investigating how the pancreas—a key organ that controls blood sugar—works differently in people with cystic fibrosis. Researchers want to understand why some people with CF develop diabetes and others don't by measuring hormone levels after participants eat a mixed meal. This information could help doctors better predict and prevent diabetes in CF patients.
Cystic fibrosis damages the pancreas over time, and many CF patients eventually develop diabetes. However, not all CF patients get diabetes, even when their pancreas is severely damaged. This study aims to understand the underlying differences in how the pancreas functions in CF, which could lead to better ways to identify who is at highest risk and how to help them.
You likely qualify if…
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You would visit the research clinic for a study visit where you'll drink a nutritional meal and have your blood drawn multiple times to measure hormone levels in response to that meal. The study compares four different groups: people without CF, people with CF but normal pancreas function, people with CF and pancreatic problems, and people with CF-related diabetes. Your participation helps researchers understand the differences between these groups.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Phase
Safety & dosing
Sponsor
University of Cincinnati
Enrollment target
~61 participants
Started
March 2023
Primary completion
July 2026
Age range
18 Years – 45 Years
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jason Winnick, PhD
University of Cincinnati
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.